Information for Healthcare Professionals


Skelaxin Safety & Side Effects

Safety and Side Effects of SKELAXIN® 800mg (metaxalone) Tablets

SKELAXIN® keeps sedation to a minimum,14 with a low incidence of side effects and drowsiness1,7

  • Less than 4% of patients taking SKELAXIN® reported drowsiness vs 1% of patients taking placebo.1
  • No interference with the motor activity used to maintain posture and balance and no loss of muscle tone11
As with all prescription medicines, there are also adverse effects.

  • Taking SKELAXIN® with food may enhance general CNS depression. Elderly patients may be especially susceptible to this effect6
  • The most frequent reactions include nausea, vomiting, gastrointestinal upset, drowsiness, dizziness, headache, and nervousness or "irritability"6